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Yoshiko Iwasaki-Ishizuka, Hideyuki Yamato, Tomoko Nii-Kono, Kiyoshi Kurokawa, and Masafumi Fukagawa
Down-regulation of parathyroid hormone receptor gene expression and osteoblastic dysfunction associated
with skeletal resistance to parathyroid hormone in a rat model of renal failure with low turnover bone
Nephrology Dialysis and Transplantation 20（2005）1904-1911
Motozo Yamashita, Sai-Xia Ying, Gen-mu Zhang, Cuiling Li, Steven Y. Cheng, Chu-xia Deng, and Ying E. Zhang
Upiquitin Ligase Smurf1 Controls Osteoblast Activity and Bone Homeostasis by Targeting MEKK2 for Degradation
Cell 121（2005）101-113
Yoshiko Iwasaki-Ishizuka, HideyukiYamato,Hisashi Murayama, Ikuko Ezawa, Kiyoshi Kurokawa, and Masafumi Fukagawa
Menatetrenone rescues bone loss by improving osteoblast dysfunction in rats immobilized by sciatic neurectomy
Life Sciences 76（2005）1721-1734
Toru Akune, Shinsuke Ohba, Satoru Kamekura, Masayuki Yamaguchi, Ung-il Chung, Naoto Kubota, Yasuo Trauchi, Yoshifumi Harada, Yoshiaki Azuma, Kozo Nakamura, Takashi Kadowaki, and Hiroshi Kawaguchi
PPARγ insufficiency enhances osteogenesisi through osteoblast formation from bone marrow progenitors
J Clin. Invest. 113（2004） 846-855
Junko Suzuki, Tohru Ikeda, Hiroyuki Kuroyama, Sachiko Seki, Michiyuki Kasai, Masanori Utsuyama, Masashi Tatsumi, Hiroshi Uematsu, and Katsuiku Hirokawa
Regulation of osteoclastogenesis by three human RANKL isoforms expressed in NIH3T3 cells
Biochemical and Biophysical Research Communications 314（2004） 1021-1027
Tohru Ikeda, Michiyuki Kasai, Junko Suzuki, Hiroyuki Kuroyama, Sachiko Seki, Masanori Utsuyama, and Katsuiku Hirokawa
Multimerization of the Receptor Activator of Nuclear Factor-kB Ligand（RANKL） Isoforms and Regulation of Osteoclastogenesis
THE JOURNAL OF BIOLOGICAL CHEMISTRY Vol.278, No.47, 47217-47222（2003）
Junichiro J.Kazama, Yoshiko Iwasaki, Hideyuki Yamato, Hisashi Murayama, Masami Sato, Fumitake Gejyo, Kiyoshi Kurokawa, and Masafumi Fukagawa
Microfocus Computed Tomography Analysis of Early Changes in Bone Microstructure in Rats with Chronic Renal Failure.
Nephron Exp Nephrol 2003; 95: e152-e157
Sunhwa Kim, Takako Koga, Miho Isobe, Britt E. Kern, Taeko Yokochi, Y. Eugene Chin, Gerard Karsenty, Tadatsugu Taniguchi, and Hiroshi Takayanagi
Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation.
GENE & DEVELOPMENT 17:1979-1991（2003）
Yoshiko Iwasaki, Hideyuki Yamato, Hisashi Murayama, Masami Sato, Takeshi Takahashi, Ikuko Ezawa, Kiyoshi Kurokawa, and Masafumi Fukagawa
Combination use of vitamin K2 further increases bone volume and amel iorates extremely low turnover bone induced by bisphosphonate therapy in tail-suspension rats.
J. Bone Miner Metab 21:154-160（2003）
Toru Akune, Naoshi Ogata, Kazuto Hoshi, Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, Hideko Takagi, Yoshiaki Azuma, Takashi Kadowaki, Kozo Nakamura, and Hiroshi Kawaguchi
Insulin Receptor Substrate-2 Maintains Predominance of Anabolic Functionover Catabolic Function of Osteoblasts.
J. of Cell Biology 159, 147-156（2002）
Yoshiko Iwasaki, Hideyuki Yamato, Hisashi Murayama, Takeshi Takahashi, Ikuko Ezawa, Kiyoshi Kurokawa, and Masafumi Fukagawa
Menatetrenone Prevents Osteoblast Dysfunction in Unilateral Sciatic Neurectomized Rats.
Jpn. J. Pharmacol. 90, 88-93（2002）
Hiroshi Takayanagi, Sunhwa Kim, Koichi Matsuo, Hiroshi Suzuki, Tomohiko Suzuki, Kojiro Sato, Taeko Yokochi, Hiromi Oda, Kozo Nakamura, Nobutaka Ida, Erwin F. Wagner, and Tadatsugu Taniguchi.
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β "
Nature 416, 744-749 （2002）.
Yoshiko Iwasaki, Hideyuki Yamato, Hisashi Murayama, Masami Sato, Takeshi Takahashi, Ikuko Ezawa, Kiyoshi Kurokawa, and Masafumi Fukagawa.
Combination use of vitamin K2 further increases bone volume and amel iorates extremely low turnover bone induced by bisphosphonate therapy in tail-suspension rats.
J. Bone Miner Metab 21:154-160（2003）
Toru Akune, Naoshi Ogata, Kazuto Hoshi, Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, Hideko Takagi, Yoshiaki Azuma, Takashi Kadowaki, Kozo Nakamura, and Hiroshi Kawaguch
Insulin Receptor Substrate-2 Maintains Predominance of Anabolic Functionover Catabolic Function of Osteoblasts.
J. of Cell Biology 159, 147-156（2002）
Yoshiko Iwasaki, Hideyuki Yamato, Hisashi Murayama, Takeshi Takahashi, Ikuko Ezawa, Kiyoshi Kurokawa, and Masafumi Fukagawa
Menatetrenone Prevents Osteoblast Dysfunction in Unilateral Sciatic Neurectomized Rats.
Jpn. J. Pharmacol. 90, 88-93（2002）
Hiroshi Takayanagi, Sunhwa Kim, Koichi Matsuo, Hiroshi Suzuki, Tomohiko Suzuki, Kojiro Sato, Taeko Yokochi, Hiromi Oda, Kozo Nakamura, Nobutaka Ida, Erwin F. Wagner, and Tadatsugu Taniguchi.
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-β "
Nature 416, 744-749 （2002）.
Yoshiko Iwasaki, Hideyuki Yamato, Hisashi Murayama, Masami Sato, Takeshi Takahashi, Ikuko Ezawa, Kiyoshi Kurokawa, and Masafumi Fukagawa.
Maintenance of trabecular structure and bone volume by vitamin K2 in mature rats with long-term tail suspension.
J. Bone Miner. Metab. 20, 216-222 （2002）.
Yoshiko Ishimi, M.Yoshida, S.Wakimoto, J.Wu, H.Chiba, X.Wang, K.Takeda, and Chisato Miyaura.
Genistein, a Soybean Isoflavone, Affects Bone Mallow Lymphopoiesis and Prevents Bone Loss in Castrated Male Mice.
Bone, 31, 180-185（2002）.
Xinxiang Wang, Jian Wu, Yoshihiro Shidoji, Yasutoshi Muto, Nobuko Ohishi, Kunio Yagi, Sachie Ikegami, Toshimasa Shinki, Nobuyuki Udagawa, Tatsuo Suda, Yoshiko Ishimi.
Effects of Geranylgeranoic Acid in Bone: Induction of Osteoblast Differentiation and Inhibition of Osteoclast Formation.
J.Bone and Mineral Research, 17, 91-100（2002）.
Y. Koshizuka, S. Ikegawa, M. Sano, K. Nakamura and Y. Nakamura
Isolation of novel mouse genes associated with ectopic ossification by differential display method using ttw, a mouse model for ectopic ossification
Cytogenet Cell Genet 94:163-168（2001）
Y.Koshizuka, S.Ikegawa, M.Sano, K.Nakamura and Y.Nakamura
Isolation of novel mouse genes associated with ectopic ossification by differential display method uding ttw, a mouse model for ectopic ossification.
Cytogenet Cell Genet 94:163-168（2001）
Naoko Yagishita, Yoko Yamamoto, Tatsuya Yoshizawa, Keisuke Sekine, Yoshikatsu Uematsu, Hisashi Murayama, Yumiko Nagai, Wojciech Krezel, Pierre Chambon, Toshio Matsumoto, and Shigeaki Kato.
Aberrant Growth Plate Development in VDR/RXRγ Double Null Mutant Mice.
Endocrinology, 142, 5332-5341（2001）.
Hiroshi Kawaguchi, Noriyo Manabe, Chisato Miyaura, Hirotaka Chikuda, Kozo Nakamura, and Makoto Kuro-o.
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia.
J. Clin. Invest. 104, 229-237 （1999）.
Yumiko Nagai, Hideyuki Yamato, Keiko Akaogi, Kunitaka Hirose, Yoshito Umeyama Kyoji Ikeda, Toshio Matsumoto, Toshiro Fujita, and Etsuro Ogata.
Role of Interleukin-6 in Uncoupling Parathyroid Hormone-Related Peptide and Interleukin-6.
J.Bone and Mineral Research, 13, 664-671（1998）.
Junichiro Kazama, Masafumi Fukagawa, Hung Yi, Miki Kumagai, Hideyuki Yamato, Nobuyuki Taniguchi, Fumitake Gejyo, Masaaki Arakawa, Hidehiro Ozawa, and Kiyoshi Kurokawa.
24R,25-Dihydroxyvitamin D3 ameliorates the high-turnover bone diseases without suppressing parathyroid function in chronic renal failure in rats.
Nephrology, 2, 361-366（1996）.
Akeo Ono, Hiroyuki Tanaka, Tomoo Yamate, Yumiko Nagai, Toshitaka Nakamura, and Yoshiki Seino.
24R,25-Dihydroxyvitamin D3 Promotes Bone Formation without Causing Excessive Resorption in Hypophosphatemic Mice.
Endocrinology, 137, 2633-2637（1996）.
Hideyuki Yamato, Yumiko Nagai, Daisuke Inoue, Yasuyuki Ohnishi, Yoshito Ueyama, Hideto Ohno, Toshio Matsumoto, Eturo Ogata, and Kyoji Ikeda.
In Vivo Evidence for Progressive Activation of Parathyroid Hormone-Related Peptide Gene Transcription with Tumor Growth and Stimulation of Osteoblastic Bone Formation at an Early Stage of Humoral Hypercalcemia of Cancer.
J.Bone and Mineral Research, 10, 36-44（1995）
Toshitaka Nakamura, Katsumi Suzuki, Yoru Hirai, T. Kurokawa, and H.Orimo.
Increased Bone Volume and Reduced Bone Turnover in Vitamin D-Replete Rabbits by the Administration of 24R,25-Dihydroxyvitamin D3.
Bone, 13, 229-236（1992）.
Toshitaka Nakamura, Yumiko Nagai, Hideyuki Yamato, Katsumi Suzuki,and Hajime Orimo.
Regulation of Bone Turnover and Prevention of Bone Atrophy in Ovarectomized Beagle Dogs by the Administration of 24R,25（OH）2D3.
Calcif. Tissue Int. 50, 221-227（1992）.
Nakamura, T.Kurokawa and H.Orimo
Increased Mechanical Strength of the Vitamin D-Replete Rat Femur by the treatment with a Large Dose of 24R,25（OH）2D3.
Bone, 10, 117-123（1989）